Initiation of Therapy When estrogen is prescribed for postmenopausal woman with uterus, progestin should also be initiated to reduce the risk of endometrial cancer. Since you may also need to take calcium and vitamin supplements and make lifestyle changes, consult your doctor for specific advice. In addition, mammography examinations ostaa estraderm ei laakemaaraykset should be scheduled based on patient age, risk factors, and prior mammogram results. Estrogens may cause an exacerbation of asthma, diabetes mellitus, epilepsy, migraine or porphyria, systemic lupus erythematosus, and hepatic hemangiomas and should be used with caution in women with these conditions. Two thousand three hundred and twenty one women from the original HERS trial agreed to participate in an open label extension of HERS, HERS II. When prescribing solely for the treatment of symptoms of vulvar and vaginal atrophy, topical vaginal products should be considered.